| Bioactivity | [D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis[1][2]. | ||||||
| Name | [D-Trp8]-γ-MSH | ||||||
| CAS | 321351-81-9 | ||||||
| Sequence | Tyr-Val-Met-Gly-His-Phe-Arg-{d-Trp}-Asp-Arg-Phe-Gly | ||||||
| Shortening | YVMGHFR-{d-Trp}-DRFG | ||||||
| Formula | C74H99N21O16S | ||||||
| Molar Mass | 1570.77 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
[D-Trp8]-γ-MSH
CAS: 321351-81-9 F: C74H99N21O16S W: 1570.77
-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for
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